Getting a solid guitar sound in your mix can be frustrating. I know it's not easy, so here are a few tips to help you along the right path to make your guitars big and loud.
First, track your guitar as you normally would. Use a little bit of EQ were some effects and you're done. That was easy.
Next, record your guitar again as a second take. This time change a few of the settings on your amp or choose a different pick up on your guitar. This will give you a new tone that will help separate the sounds of the guitar when you go to mix the tracks.
Now do a third take and this time use an EQ to pull out the bottom of the tone. Give this guitar an effect that sounds like it's on the radio by filtering out everything below 250 Hz.
Pan the first two takes slightly right and left in the mix. Adjust compression as needed and you should be getting a bigger sound out of your guitar mix.
Please leave a comment if you'd like more info on this technique.